Photo: Europa Press
(Caracas, 10 November – Europa Press). – Drinking coffee during breakfast not only increases energy and attention, but also can protect against the development of both Alzheimer's and Parkinson's disease, according to new research carried out by the Brain Institute of Krembil, in Toronto (Canada).
"Coffee consumption seems to have some correlation with a lower risk of developing Alzheimer's and Parkinson's disease," explains Dr. Donald Weaver, co-director of the Brain Kremlin Institute. But we wanted to investigate why this is happening, what relationships are involved and how they can affect the cognitive decline associated with age. "
Dr. Weaver used the help of Dr. Ross Mancini, a researcher in medical chemistry and biologist Yanfei Wang. Examine three different types of coffee: lightly roasted, dark roasted and dark roasted decaffeinated.
"Both decaffeinated caffeine and dark roast and decaffeinated had the same potential in our initial experimental tests, so from the very beginning we observed that its protective action can not be caused by caffeine" – he explains.
Dr Mancini then identified a group of compounds known as phenylindans that arise from the roasting process of coffee beans. Fenilindanos are unique because they are studied in a study that prevents the grouping of both beta amyloid and tau, two fragments of common proteins in Alzheimer's and Parkinson's disease. "So phenylindans are a double inhibitor, that's very interesting and we did not expect it." Doctor Weaver admits.
Because roasting coffee generates higher amounts of phenylindan, the dark baking appears to be more protective than light burning. "For the first time, someone is studying how phenylalanine interacts with proteins responsible for Alzheimer's and Parkinson's disease," says Dr. Mancini. The next step would be to examine to what extent these compounds are beneficial and whether they have the ability to reach the bloodstream or cross the blood-brain barrier. "
The fact that it is a natural relationship compared to a synthetic one is also a great advantage, admits Dr. Weaver. But He admits that more research is still needed before they can be translated into possible therapeutic options. "What's happening in this study is taking epidemiological evidence and shows that there really are coffee ingredients that are beneficial to prevent cognitive decline." It's interesting, but are we suggesting that coffee is a medicine? Absolutely not, "he warns.